Keep them safe and out of the reach of children. It can also take several weeks or months to reverse bad sleeping habits caused by Arimidex. Always take the pills exactly as your nurse or pharmacist has told you. They can normally suggest ways to improve the side effects. If you’re having chemotherapy or radiotherapy, your specialist will tell you when it’s best to start letrozole. 4. Sometimes it may be possible to change to another hormone drug. Many types of breast cancer depend on the hormone estrogen to grow. Sometimes it may … Let your doctor or nurse know if this happens. There are a number of other brands of letrozole, all of which contain the same dose of the drug. If hot flashes are troublesome: • Try taking your letrozole at bedtime. Some people worry about stopping their treatment, but there’s evidence that letrozole continues to reduce the risk of breast cancer coming back for many years after you stop taking it. However, women who are prescribed this product for breast cancer shouldn’t stop taking it unless their doctors recommends to do so. Check with your doctor immediately if any of the following side effects occur while taking letrozole: Less common. Research has shown that about 25% of women who are prescribed hormonal therapy to reduce the risk of recurrence after surgery either don’t start taking the medicine or stop taking it early, in many cases because of side effects. In rare cases, women may have vaginal bleeding. Withdrawal: Consult your gynecologist for a better way to discontinue your hormones. You should not stop taking Letrozole without discussing with your physician. Talk to your doctor if side effects from Arimidex are persisting despite stopping it. Always tell your doctor or nurse about any change to your eyesight. Tell your doctor or nurse if this is a problem. when you first start taking letrozole. Or they may have difficulty concentrating or may feel anxious or have trouble sleeping. It can cause mild withdrawal symptoms that can include the following:-Dizziness-Nausea-Headache-Sweating-Depression-Insomnia. Non-hormonal creams and gels or lubricants can help reduce vaginal dryness and discomfort during sex. Less common but more severe side effects of aromatase inhibitors are heart problems, osteoporosis, and broken bones. How long will I have to take it? Talk to your nurse or doctor if you experience these changes so that they can give you support and. If you have a loss of bone density, or 'brittle bones' - a condition known as osteoporosis. Given that one in three patients taking tamoxifen or aromatase inhibitors eventually develop resistance, the researchers … Taking letrozole for a number of years increases the risk of bone thinning (osteoporosis). 54 years experience Neurosurgery. If you’re taking letrozole to treat breast cancer that has come back or spread to another part of the body, you’ll usually take it for as long as it’s keeping the cancer under control. Learn about side effects, warnings, dosage, and more. It is normally taken over a number of years. However, not taking the drug for the recommended time may increase the risk of your breast cancer coming back. 2. No one responded to my post about this, so I'll try again: I've only been taking Femara, but I'm already wondering: so what happens in 5 or 10 years (new research shows we might have to be on this stuff longer) when we stop taking our aromatase inhibitors? It blocks this process and reduces the amount of estrogen in the body. Tell your doctor if your hot flashes become bothersome. Taking regular walks, eating a healthy diet, not smoking, and following guidelines for drinking alcohol will also help strengthen your bones. Your doctor may check your cholesterol levels with a blood test. What is letrozole? However, some side effects, such as high cholesterol, lymphedema, osteoporosis, and vaginal dryness may persist despite discontinuation of Arimidex. Taking letrozole with other drugs. This is normally mild. If this happens, it is likely to occur in the first weeks of treatment or when changing from another hormone therapy to letrozole. Do not take other drugs containing oestrogen, such as hormone replacement therapy (HRT), while you’re taking letrozole as this may interfere with its effectiveness. Do not use if you are pregnant. They can give you drugs to help. Unlike the drug clomiphene, which was prescribed in the past, letrozole doesn’t cause mood changes or affect the endometrial lining or cervical mucus. Let your doctor or nurse know if you have headaches. Casper says that about 1 percent of people who take letrozole get leg cramps and headaches, but the good news is that these symptoms go away once you stop taking the pills. Most side effects settle down a few months after taking letrozole or can be controlled or managed. Men with breast cancer may be given letrozole, although another drug called tamoxifen is more commonly used. You may have pain or stiffness in the joints, or sometimes in your muscles. You may experience some of the side effects mentioned here, though it is rare for a patient to have all of them. It can help to lower your intake of nicotine, alcohol, and hot beverages containing caffeine such as tea and coffee. Dr. Edward Smith answered. • If night sweats interfere with sleep, try taking your letrozole in the morning. Hormones are substances produced naturally in the body. If you forget to take a pill, take one as soon as you remember. Keep using birth control for at least 3 weeks after your last dose of letrozole. This may increase the risk of bone fractures. #1 is a problem with my hands, unable to make fists or grip a knife to cut meat, hands feeling swollen every morning. Your nurse will monitor it regularly during treatment. Always inform your doctor or nurse of the side effects you experience. Tell your doctor if this does not get better. Hospital Universitario Fundación Jiménez Díaz, Strategic plan of the Oncohealth Institute. Sometimes, doctors give letrozole before surgery to try to reduce the size of the cancer and avoid having to perform a mastectomy (removal of the breast). Do not stop: Letrozole ... Hi, i stopped taking femara (letrozole) two weeks ago - cold turkey and have been having a lot of headaches, dizziness, nausea, muscle and joint pains, tiredness? Except when it is almost time for your next dose, do not take a double dose. Hormone therapies interfere with the way hormones are made or formed in the body. These act as chemical messengers and help control the activity of cells and organs. This includes your doctors, nurses, pharmacists, and dentists. If you accidentally take too much letrozole (Femara), contact a doctor or hospital straight away.You might need medical treatment. Do not stop taking letrozole unless your doctor instructs you to. However, not taking the drug for the recommended time may increase the risk of your breast cancer coming back. Now 2 months later, without letrozole I am feeling much better. Get a new prescription before the one you have runs out, and keep track of holidays, when pharmacies may be closed. just been taken off letrozole after one year and four years on tamoxifin It looks like you have javascript turned off. Let your doctor know if you have pain or discomfort when urinating, if you urinate more frequently than normal, or if your urine is cloudy or foul-smelling. This medicine may make you dizzy, drowsy, or tired than they are normally. Dress in layers so you can remove clothing if you need to. Doctors sometimes prescribe it before or after another type of hormone therapy. Posted: December 2, 2011; If you would like to reproduce some or all of this content, see Reuse of NCI Information for guidance about copyright and permissions. I stopped taking it a month ago cause My hips and shoulders felt like they were coming out my sockets. Both tamoxifen and aromatase inhibitors can cause side effects. Find out more about the side effects of letrozole. Posts: 446 Joined: Jan 2008 Apr 10, 2009 - 5:23 pm. It is also used to treat early breast cancer in women who have experienced menopause and who have already been treated with a medication called tamoxifen (Nolvadex) for 5 years. Do not start, stop, or change the dose of any drug without checking with your doctor. Less pain in the knees but still getting better gradually. 8. One more time/what happens when you stop AIs. I hope this … Letrozole is used treat early breast cancer in women who have experienced menopause (change of life; end of monthly menstrual periods) and who have had other treatments, such as radiation or surgery to remove the tumor. If you’re thinking about stopping taking letrozole for any reason, talk to your specialist first. #2 is possibly just the inability to bounce … Some people worry about stopping their treatment, but there’s evidence that exemestane continues to reduce the risk of breast cancer coming back for many years after you stop taking it. If your cancer is hormone receptor negative, then letrozole will not be of any benefit. I hope this helps. These include complementary therapies and herbal remedies. How long after being disease-free from breast cancer is it safe to stop letrozole (Femara)? If you have any questions about this, talk to your doctor. Where to Purchase Femara (Letrozole)? They should be stored away from heat and direct sunlight. Talk to your specialist, pharmacist or GP about any complementary therapies, herbal remedies or supplements you want to use before you start using them. When letrozole is given However, not taking the drug for the recommended time may increase the risk of your breast cancer coming back. I know it's scary but I had an allergic reaction to letrozole and had to stop taking all my medication including my in gales and lanzaporole and then slowly introduced them back but not the letrozole I have now been put on exemestane and yes still have joint pain but if it's to bad I take paracetamol. Letrozole may cause dizziness. You won’t need to stop taking it gradually. It can also be given to treat breast cancer that has spread to another part of the body (secondary breast cancer), when it’s often given alongside another drug. 1. It is very important that you contact your doctor immediately if you develop a sever rash. You can buy these from a chemist, or your doctor can prescribe them. You may have bleeding when you start this treatment, or if you change to it from another treatment. You should take the right dose, not more or less. Here, we explain the most common side effects of letrozole. Occasionally, letrozole may be used as the first treatment for breast cancer, for example when surgery isn’t appropriate or needs to be delayed. In this section, you can read about why it's so important to stick to your treatment plan and ways to handle possible difficulties in following radiation, chemotherapy, and hormonal therapy regimens. The amount of Letrozole that you will receive depends on many factors, including your general health or other health problems, and the type of cancer or condition being treated. It is very important that you do not stop taking letrozole without telling your doctor, as this may affect the success of the treatment. Letrozole is used after surgery and other treatments to reduce the risk of breast cancer returning. It’s sometimes given before surgery to shrink a larger breast cancer. Some women find that their appetite increases. Letrozole can also be used to treat breast cancer that has come back (recurrence). Some breast cancers are stimulated to grow by the hormone oestrogen. Instead it's made in the fatty tissues of the body. If you have any problems with the way your liver works, or any problems with the way your kidneys work. • Some people find it helpful by avoiding alcohol, spicy food, caffeine intake (coffee, tea, colas, chocolate). Letrozole can harm an unborn baby. Bone fracture; breast pain; chest pain What are some things I need to know or do while I take Letrozole? After menopause, estrogen is no longer made in the ovaries. You may gain weight when taking hormone therapy. Taking short walks regularly will help you feel less tired. Letrozole can also cause indigestion or abdominal pain. Tell your doctor if you notice this or any other type of swelling. Your treatment team will tell you when to stop taking letrozole. The half life of the drug is 2 days so it should be out of your system within 4 days. Sometimes, women have irritated eyes or blurred vision when taking letrozole. "If the side effects from letrozole are intolerable, benefits are maintained by switching to tamoxifen rather that stopping hormonal therapy altogether." You should not use letrozole if you are allergic to it. You can use non-hormonal creams, gels or lubricants to help with vaginal dryness and any discomfort during sex. The level of drug in your body will remain high enough from the day before. Some people worry about stopping their treatment, but there’s evidence that letrozole continues to reduce the risk of breast cancer coming back for many years after you stop taking it. If this happens, your doctor may give you medicine to lower the cholesterol and fat in the blood. It is used to treat breast cancer in women who have gone through menopause. Talk to your specialist or advice line before you stop taking a cancer drug. You may develop a mild skin rash. This is why, this product can be stopped abruptly. Before taking this medicine. I completed the full five years as prescribed. There is hope after this med! Letrozole is a product that generally do not need to be stopped taking it gradually. Registered Office: Fifth Floor, Ibex House, 42-47 Minories, London EC3N 1DY. If you miss a dose, you don’t need to take an extra dose the next day. What happens when you stop taking Letrozole? However, they may be more problematic for some women. These drugs are often prescribed after breast cancer surgery, chemotherapy or radiation therapy to help prevent a recurrence of the disease. Do not stop taking letrozole unless your doctor instructs you to. Aromatase inhibitors may cause muscle and joint aches and pains. Why Buy Letrozole? I had an estrogen cancer and I have been on letrozole for a year. There are certain important things to remember when taking the tablets. This medicine may increase the amount of cholesterol and fat in the blood. Tell your doctor if you are taking any other medication. You won’t need to stop taking it gradually. His feeling was that as there is no evidence that continuing Letrozole after 5 years is beneficial, I should stop taking it after December. If you have any worries or questions about taking or stopping letrozole, you can call us free on 0808 800 6000 to talk through your concerns. The pills are taken at the same time each day, either in the morning or at night. This includes medications that can be purchased in a store or pharmacy. If letrozole stops working, your specialist may prescribe another hormone drug. This will depend on your individual circumstances, but letrozole is usually taken for five to ten years. HOT FLASHES AND SWEATING. A study reports on the results of several different studies looking at how often side effects made women stop taking hormonal therapy. It can help to lower your intake of nicotine, alcohol, and hot beverages containing caffeine such as tea and coffee. Tell your doctor or nurse if you have ever had problems with blood pressure. Some people start taking letrozole after a few years of taking the hormone therapy drug tamoxifen. I have another appt booked at the oncology clinic in early December so I will talk further about it with whomever I see at that time. If you’re thinking about stopping taking letrozole for any reason, talk to your specialist first. How it’s taken  If you notice any changes in your heart rate, tell your doctor immediately. This type of breast is called estrogen receptor-positive (ER-positive) breast cancer. 7. Always let your dentist know that you are taking letrozole. Your doctor will determine your dose and how long you will be taking Letrozole. If you have pain or pressure in your chest or feel out of breath at any time during or after treatment, let your doctor know immediately. Your hair will thicken after the treatment ends. Stopping Letrozole? This is important to ensure that it is working as well as possible. Some women notice that their hair thins out while they are taking letrozole. Eating healthy meals and becoming more physically active can help you maintain a healthy weight. It the side effects are very bothersome and are unmanageable, your oncologist may suggest you start on a different hormone therapy. Yes this is a common reaction when you stop taking Femara. Hormone therapy is a very common treatment for secondary breast cancer and many people take it for a long time. The study also looked at how stopping hormonal therapy affected the women's risk of dying. How does letrozole work? Sometimes letrozole is given alongside a drug called goserelin (Zoladex) to women who haven’t yet been through the menopause. 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