18883-66-4. To monitore blood glucose concentrations, blood was collected from the tail vein of the rats. .. 121 °C (Decomposes) Sigma-Aldrich SIGMA-S0130: Experimental LogP:-1.413 LabNetwork LN01795997: Experimental Solubility: 10 mM in DMSO MedChem Express HY-13753: Miscellaneous. Therapeutisch dient es als Zytostatikum zur Behandlung von als Insulinomen bezeic… Sodium citrate and citric acid are combined until a pH of 4.5-5.5 is obtained. Streptozocin  stz  Streptozotocin  Monitor glucose level for onset of hyperglycemia. 100mg.          ¥280 >10 S0130. Toxicity: Organic Compound; Amine; Drug; Antineoplastic Agent; Antibiotic; Antibiotic, Antineoplastic; Metabolite; Synthetic Compound Toxin, Toxin-Target Database T3D2788: Safety: Danger Biosynth W-201687: GHS08 … (18–20 g, 8 weeks) were intraperitoneally injected with 50 mg/kg STZ (S0130, Sigma-Aldrich, Burlington, MA, USA) daily for 5 consecutive days to induce type 1 DM [2]. أ Sigma ţ S0130 װ ṩ ƣ 1g 100Ԫ ֻ ֵ 500mg 50Ԫ ֵ ۼ ͣ ֹʱ Ϊ 201 3 12 30 ֹ CAS ؼ S0130. Mengeneinheit: 1X100MG. Procedures were carried out in accordance with the regulations of the United Kingdom Animals (Scientific Procedures) Act 1986 and/or United Arab Emirates. STZ is more typically used to induce Type I diabetes as it damages the pancreatic beta-cells. ¥280 >10 S0130. ¥280 >10 S0130. Summenformel: C8H15N3O7. ¥491. ¥280 >10 S0130. S0130 CAS NUMBER: 18883-66-4 SYNONYM: Streptozocin PHYSICAL DESCRIPTION: Appearance: White to yellow powder Molecular formula: C 8H 15N 3O 7 Molecular weight: 265.2 Melting point: Decomposes at 115ΕC if anhydrous.1 Although Sigma does not determine a value, water content should be # 3%.2 EmM(228nm) = 6.36 (ethanol) Optical rotation: +39Ε(equilibrium of α, ß anomers in … S0130 Sigma. Areas where STZ is prepared and/or administered MUST be cleaned and decontaminated immediately following each procedure. þÎñµç»°£º4006-111-883    administration to avoid vomiting. 18883-66-4. Monitor glucose level for onset of hyperglycemia. Streptozocin (STZ) shows higher cytotoxic effect in vitro on hematological cell lines compared to Alloxan (ALX). Weigh Streptozocin (Sigma 85882) and store at -20ºC in aliquots (~1.25 mg/mouse assuming body weight of 25 g. For example, if we have 3 mice weight 25 g, we will need about 3.75 mg of STZ 18883-66-4. Control rats were applied isotonic saline intraperitoneally. Hyperglycemia and ICH Model Diabetic model was induced by intraperitoneal injection with streptozotocin (STZ; Sigma-S0130, Sigma–Aldrich Trading Co., Ltd., Shanghai, China) at 60 mg/kg for 3 days before operation ( ). أ Sigma ţ S0130 װ ṩ ƣ 1g 100Ԫ ֻ ֵ 500mg 50Ԫ ֵ ۼ ͣ ֹʱ Ϊ 201 3 12 30 ֹ CAS ؼ S0130. Streptozocin Sigma. *Please select more than one item to compare Citrate buffer-injected mice served as nondiabetic controls. Mice with a basal blood glucose level of more than 250 mg/dL were considered diabetic and included in experiments. Use reagent-grade materials obtainable from various commercial vendors such as Sigma-Aldrich. Reagent Preparation: (This area may have several differe nt preparations with the table Diabetes was induced in 8-week old mice with intraperitoneal administration of streptozotocin (STZ, Sigma S0130, dissolved in 0.1 M citrate buffer, PH 4.5) at 50mg/kg after 4-6 hours of food deprivation each day for 5 consecutive days. An N-nitroso-containing diabetogenic compound that acts as a nitric oxide donor in pancreatic islets. The total amount of STZ administered per individual corresponded to 150mg/kg BW. Search results for stz at Sigma-Aldrich. أ Sigma ţ S0130 װ ṩ ƣ 1g 100Ԫ ֻ ֵ 500mg 50Ԫ ֵ ۼ ͣ ֹʱ Ϊ 201 3 12 30 ֹ CAS ؼ S0130. ¥280 >10 S0130. Streptozotocin Sigma S0130 Sodium Citrate Sigma 71402 Citric acid Sigma C1909 Protocol: 1. Methods Materials STZ was obtained from Sigma-Aldrich Inc. (Sigma, S0130, USA). 2. ELISA kits for mouse MCP-1 … 2-واردات انواع محیط کشت های آزمایشگاهی. STR201.100. ADVANCED SEARCH; STRUCTURE SEARCH; CERT OF ANALYSIS; SDS SEARCH 43 Wistar male rats aged 16 weeks were used. Synonyme: 2-Deoxy-2-(3-methy1-3-nitrosoureido)-D-glucopyranose, N-D-Glucosyl-(2)-N'-nitroso-N'-methylurea, NSC 85998, Streptozocin ALX appeares not to be toxic for the studied cell lines with estimated IC 50 values of 2809, 3679 or over 4000 μg/mL for HL60, K562 and C1498 cells, respectively. 100 mg of STZ (Sigma‐S0130) was first dissolved into 5 mL of saline, and then add to 15 mL cold saline to a final volume of 20 mL. Streptozocin Sigma. STREPTOZOTOCIN , 100mg … Group 3 was given 5 mg/kg glibenclamide, a standard oral hypoglycemic agent, in thesame vehicle. Search results for S0130-1G at Sigma-Aldrich. 10 weeks after diabetes induction, mice were given ATG (Cayman Chemicals) dissolved in 5% … HCQ (HY-B1370) and CCCP (HY-100941) were purchased from MedChemExpress. Reagent Preparation: (This area may have several differe nt preparations with the table Weigh Streptozocin (Sigma 85882) and store at -20ºC in aliquots (~1.25 mg/mouse assuming body weight of 25 g. For example, if we have 3 mice weight 25 g, we will need about 3.75 mg of STZ Mice were considered diabetic with fast-ing blood glucose ≥16.7 mmol/L in two consecutive ana-lyses conducted one week after STZ administration. 021-34615995/021-34615975/021-34619803, ¹Ø¼ü×Ö£º ¥491. Á´ëå×ô¾úËØ Protocol. Diabetes was confirmed by measuring the venous circulating plasma concentrations of glucose. For the diabetic model, the mice were intraperitoneally injected with a single dose (150 mg/kg body weight) of streptozotocin (STZ) (Sigma s0130, USA). أ Sigma ţ S0130 װ ṩ ƣ 1g 100Ԫ ֻ ֵ 500mg 50Ԫ ֵ ۼ ͣ ֹʱ Ϊ 201 3 12 30 ֹ CAS ؼ S0130. 100mg. If you wish, you may consider the option of using alloxan instead. أ Sigma ţ S0130 װ ṩ ƣ 1g 100Ԫ ֻ ֵ 500mg 50Ԫ ֵ ۼ ͣ ֹʱ Ϊ 201 3 12 30 ֹ CAS ؼ S0130. 100mg. For the diabetic model, the mice were intraperitoneally injected with a single dose (150 mg/kg body weight) of streptozotocin (STZ) (Sigma s0130, USA). Quercetin (15 mg/kg, live weight/day) (Sigma Q4951) were injected intraperitoneal to the Q and DQ groups (after diabetes had happened) during 4 week. 2.3 | Insulin treatment of diabetic monkeys Insulin treatment was performed as previously described. Streptozocin Sigma. Herstellernummer: S0130-1G. Description: Streptozotocin (STZ, NSC-85998, Streptozocin) is a glucosamine-nitrosourea derivative, which is a DNA-methylating, carcinogenic, antibiotic and diabetes inducing agent.Streptozotocin induces autophagy and apoptosis. Mice in the Control group received an equivalent volume of saline via the same route. Aqueous solutions of STZ are not stable and rapidly undergo mutarotation to an equilibrium mixture of alpha- and beta-anomers. An antibiotic effective against Gram-negative bacteria. View information & documentation regarding Streptozocin, including CAS, MSDS & more. STREPTOZOTOCIN , 500mg (BioShop) View Detail Add to Order. STZ-induced T1D mice were generated as previously described.9 In brief, STZ (Cat #S0130, Sigma-Aldrich, St Louis, Missouri) was dissolved in 0.05 M sodium citrate buffer and intraperitoneally injected into male C57BL/6J mice (4–5 weeks old) at a dose of 55 mg/kg body weight (mpk) daily for 5 days. 2. Diabetic model was induced by intraperitoneal injection with streptozotocin (STZ; Sigma-S0130, Sigma–Aldrich Trading Co., Ltd., Shanghai, China) at 60 mg/kg for 3 … Lagertemperatur: -20C. Search results for STZ at Sigma-Aldrich. Kontakt +41 31 932 11 66; [email protected]; Dr. Grogg Chemie AG - Über uns. BLOOD COLLECTION AND BLOOD GLUCOSE DETERMINATIONS. Lagertemperatur: … Hyperglycemia was identified by polyuria and polydipsia and by measuring nonfasting plasma glucose levels 48 h after the injection; animals that did not reach … Glucose (G8270), Mannitol (78513), and STZ (S0130) were purchased from Sigma. ¥280 >10 S0130. Cari produk Lainnya lainnya di Tokopedia. أ Sigma ţ S0130 װ ṩ ƣ 1g 100Ԫ ֻ ֵ 500mg 50Ԫ ֵ ۼ ͣ ֹʱ Ϊ 201 3 12 30 ֹ CAS ؼ S0130. Streptozocin  Group 1 was the non-diabetic control group. Streptozocin Sigma. Because of the short half-life of STZ (Sigma S0130, Stockholm, Sweden), it was dissolved in 100 mmol/L disodium citrate buffer solution, pH 4.5, at a concentration of 80 mg/mL, and administered i.v. Á´ëåùËØ, ËÍ100ÔªÊÖ»ú³äÖµ¿¨£¬¶©¹º500mgËÍ50Ôª³äÖµ¿¨£¬ÀÛ¼ÆÔùËÍ£¡. (Stz) in citrate buffer (Sigma, S0130), Stz-Na model. For STZ treatments, mice were fasted overnight and then injected intraperitoneally with a single high dose of STZ (150 mg/kg) (S0130; Sigma) dissolved in 100 mmol/L citrate buffer (pH 4.5) or injected with citrate buffer alone as a control, then immediately given access to food. Virtual. *Please select more than one item to compare Diabetes was induced in 8-week old mice with intraperitoneal administration of streptozotocin (STZ, Sigma S0130, dissolved in 0.1 M citrate buffer, PH 4.5) at 50mg/kg after 4-6 hours of food deprivation each day for 5 consecutive days. فروشگاه : استرپتوزوتوسین - استرپتوزوسین - ( STZ ) - اس تی زد|کد کالای موجود از شرکت سیگما : S0130 Sigma نام فارسی کالا : استرپتوزوتوسین - استرپتوزوسین نام انگلیسی کالا : Streptozocin مشخصات عمومی محصول : ≥75% α … STZ is an easy and convenient drug model commonly used by researchers to induce diabetes mellitus in rats. Streptozocin, auch Streptozotocin (STZ) [Handelsname: Zanosar® (CH)], ist eine zu den Substanzklassen der Glucosamine und der Nitrosoharnstoffe gehörende und natürlich vorkommende chemische Verbindung, die spezifisch toxisch für die insulinproduzierenden Betazellen in den Langerhansschen Inseln der Bauchspeicheldrüse ist. Sigma No. STZ (S0130, Sigma-Aldrich, St. Louis, MO, USA) and MEL (M5250, Sigma-Aldrich) were used in the biological assays. ¥491. 100 mg of STZ (Sigma-S0130) was first dissolved into 5 mL of saline, and then add to 15 mL cold saline to a final volume of 20 mL. STREPTOZOTOCIN MIXED ANOMERS (Sigma-Aldrich) View Detail Add to Order. S0130-500MG . Streptozocin is more toxic, especially for the human myeloid leukemia cell line, HL60. Experimental Groups The diabetic animals were placed into 7 groups (1-7) of eleven rats each. Mice in the Control group received an equivalent volume of saline via the same route. Virtual. Mice were considered diabetic with fasting blood glucose ≥16.7 mmol/L in two consecutive analyses conducted one week after STZ administration. intravenously injected with STZ (Lot S0130, Sigma, USA) at 15 mg/kg (15 mg/mL dissolved in the phosphate buffer saline (PBS) solution) once every 4 weeks with a total of 8 times for hyperglycemic induction (Figure 1, bold arrows). ¥491. group and the STZ -Nc group, with 10 male mice were in each group. Hersteller: SIGMA-ALDRICH. Buy STZ streptozotocin streptozotocin 18883-66-4 Sigma S0130 100mg from newbecca, provides best taobao agent and taobao english site service, cheap purchase Scientific experiment equipment Rats that had fasted overnight were injected intraperitoneally with 230 mg/kg nicotinamide (NA; Sigma, N3376) 15 min prior to an intravenous injection of 65 mg/kg streptozotocin (STZ) in citrate buffer (Sigma, S0130). STZ was administered via the jugular vein over a 5‐min period immediately after dissolving. Clidox - 1:5:1 solution (base : water : activator) - Fume Hood or BSC 5.3.2. Bleach Solution (10%) - Floor & Cage Dunking 5.4. 2. Á´ëå×ô¾úËØ Streptozocin Sigma. 2.3. Verpackung: 1, 5 g in glass bottle 71.30 CHF 71.30 CHF Das Produkt ist nicht verfügbar. metabolism in STZ-induced diabetic rats and measured oxidative enzyme and antioxidative enzyme plasma levels to explore the possible mechanisms of catalpol on type 2 diabetes mellitus. Administer an intraperitoneal injection of streptozotocin (50 mg/kg body weight) daily for 5 days. Compare Products: Select up to 4 products. Causes DNA alkylation and DNA strand breaks in pancreatic islet cells. In some models, hyperglycemia is induced in adult rats by the administration of streptozotocin (STZ); ... a single dose of STZ (Cat. Buy STZ streptozotocin streptozotocin 18883-66-4 Sigma S0130 100mg from newbecca, provides best taobao agent and taobao english site service, cheap purchase Scientific experiment equipment .. Sicherheitsdatenblatt (andere Sprachen auf Anfrage) Zurück zur Homepage. ¥491. Compare Products: Select up to 4 products. Artikelnummer: S0130-100MG. The mice in the STZ-HFd group were injected with 0.1 M sodium citrate-hydrochloric acid buffer with 150 µg STZ (S0130; Sigma-Aldrich; Merck KGaA) 5 days after birth, and were then fed a HF d (1055.05 Kcal/100 g; protein, 19.2%; fat, 4.3%; carbohydrates, 67.3%) beginning from the age of 4 weeks. stz  Streptozotocin  دیگر فعالیت های این گروه : 1-عرضه برتر انواع مواد شیمیایی شرکت MERCK. 21 rats between 6 and 8 weeks were injected intraperitoneally with STZ (S0130, Sigma, 60 mg/kg) to induce diabetes as described previously (e.g., Howarth et al., 2008; Newton et al., 2017).          100mg. Virtual. Twenty rats were given a single intraperitoneal dose (65 mg/kg) of STZ (S0130, Sigma-Aldrich, MO) while the rest 10 rats were given a same dosage of saline. The remainder of the chemicals used were also purchased from Sigma-Aldrich. Mice in the Control group received an equivalent volume of saline via the same route. Animals were handled according to the National Institutes of Health Guide for the Care and Use of Laboratory Animals … Á´ëåùËØ, ËÍ100ÔªÊÖ»ú³äÖµ¿¨£¬¶©¹º500mgËÍ50Ôª³äÖµ¿¨£¬ÀÛ¼ÆÔùËÍ£¡. Delivered in 2 to 4 days (estimated) $189.14 Add to Order: STR201.500 . Search results for STZ at Sigma-Aldrich. Postoperative care. Glucose concentrations of control and study groups were measured by a glucometer (On-Call Plus, Acon Lab., San tDiego, USA) before and at 72 h h after STZ injection. Jual Streptozotocin STZ Merk (sigma) - 250 mg dengan harga Rp2.300.000 dari toko online potensi chemical, Kab. The total amount of STZ per individual corresponded to 150 mg/kg b.w. 18883-66-4. ADVANCED SEARCH; STRUCTURE SEARCH; CERT OF ANALYSIS; SDS SEARCH Home; Nehmen Sie Kontakt auf. STR201.500. 10 weeks after diabetes induction, mice were given ATG (Cayman Chemicals) dissolved in 5% … 100mg. 18883-66-4. Streptozotocin Sigma S0130 Sodium Citrate Sigma 71402 Citric acid Sigma C1909 Protocol: 1. Jual beli online aman dan nyaman hanya di Tokopedia. After 5 days, glucose levels were evaluated using Accu-CHECK Active (Roche Diagnostic Inc., Korea). Streptozotocin or streptozocin (INN, USP) (STZ) is a naturally occurring alkylating antineoplastic agent that is particularly toxic to the insulin-producing beta cells of the pancreas in mammals. þÎñµç»°£º4006-111-883    Metabolic features with a high correlation in non-diabetic/untreated and STZ-induced diabetic/TETA-treated rats ... (S0130 SIGMA, ≥75% α-anomer basis, ≥98% (HPLC), powder) Streptozocin? Delivered in 2 to 3 days (estimated) $118.56 Add to Order: STR201.100 . DMEM (SH30022.01, Hyclone, Logan, Utah, USA) was used to prepare 10 mM stock solution of streptozotocin (STZ) (S0130, Sigma-Aldrich, St. Louis, MO, USA). Giving (0.12 mg/kg, iv) Tropisetro hydrochloride prior to STZ administration to avoid vomiting. Diabetes was induced by administering 5 consequent dosages of streptozotocin (STZ, S0130 Sigma), dissolved in 0.05-M citrate buffer, at the concentration of 60 mg/kg body weight intraperitoneally with 24 hours interval. Weigh the appropriate amount of STZ so your final concentration in the Na-Citrate buffer will be 7.5 mg/ml and place this into an Eppendorf tube; cover with aluminum foil (light sensitive). Citrate buffer-injected mice served as nondiabetic controls. 100mg. CAS-Nummer: 18883-66-4. S0130-500MG. Herstellernummer: S0130-100MG. Due to the short half-life of STZ (Sigma S0130, Stockholm, Sweden) it was dissolved in 100mmol/L disodium citrate buffer solution, pH 4.5, at a concen-tration of 80mg/mL, and administered intravenously within 5min, while the animals were under general anaesthesia. streptozotocin (STZ) (Sigma s0130, USA). 2.3 Insulin treatment of diabetic monkeys. أ Sigma ţ S0130 װ ṩ ƣ 1g 100Ԫ ֻ ֵ 500mg 50Ԫ ֵ ۼ ͣ ֹʱ Ϊ 201 3 12 30 ֹ CAS ؼ S0130. We included two experimental protocols to induce alterations in glucose homeostasis: experimental protocol A: a single dose of STZ (Cat. ¥491. (approximately 1 mL/s) within 2 min, while the animal was under general anaesthesia. Group 2, the diabetic control group, received 1.5 ml of a physiological NaCl solution. Administer an intraperitoneal injection of streptozotocin (50 mg/kg body weight) daily for 5 days. Sigma-Aldrich offers a number of Streptozocin products. STZ and quercetin prepared freshly before the application. streptozotocin (STZ, S0130, Sigma Chemical Inc., St Louis, MO, USA ). 18883-66-4. The trizol reagent (15596026) was purchased from Invitrogen, and SYBR Green PCR master mix kit (1725201) was obtained from Bio-Rad Laboratories. For STZ treatments, mice were fasted overnight and then injected intraperitoneally with a single high dose of STZ (150 mg/kg) (S0130; Sigma) dissolved in 100 mmol/L citrate buffer (pH 4.5) or injected with citrate buffer alone as a control, then immediately given access to food. STZ (60 mg/kg, live weight (Sigma S0130-1G)) were injected intraperitoneal to the D and DQ groups as a single dose. Einzigartig – Grogg-Shop mit über 1,8 Millionen Artikeln mit den kompletten Sortimenten … Mito-TEMPO (sc-221945) was purchased from Santa Cruz Biotech. Streptozocin Sigma. ¥280 >10 S0130. Streptozotocin Sigma # S-0130 Eppendorf tube Aluminum foil Procedure Concentration: 7.5 mg/ml STZ should be stored at –20 C to avoid dessication. Aktuelle Lieferfrist auf Anfrage. أ Sigma ţ S0130 ֻ ۣ 880Ԫ /1g 1600Ԫ/2*1g 3500Ԫ/5*1g 600Ԫ/500mg 185Ԫ/100mg װ ṩ ƣ Hersteller: SIGMA-ALDRICH. In den Warenkorb. 100mg. 021-34615995/021-34615975/021-34619803, ¹Ø¼ü×Ö£º Synonyme: N-(Methylnitrosocarbamoyl)-alpha-D-glucosamine; Streptozotocin. ¥491. Streptozocin Sigma. Streptozotocin; Sodium citrate; Citric acid; 10 mM sodium citrate and 10 mM citric acid are used to create the citrate buffer as the solvent for the STZ. Hyperglycemia and ICH Model Diabetic model was induced by intraperitoneal injection with streptozotocin (STZ; Sigma-S0130, Sigma–Aldrich Trading Co., Ltd., Shanghai, China) at 60 mg/kg for 3 days before operation ( ). Type 1 diabetes is usually induced by a single intraperitoneal injection (55 mg/kg) of STZ (S0130 Sigma–Aldrich; dissolved in citrate buffer pH 4.5). DMSO (D2650, Sigma-Aldrich, St. Louis, MO, USA) was used to prepare 10 mM stock solution of donepezil (D6821, Sigma-Aldrich, St. Louis, MO, USA), which was filtered and preserved at −20°C. Aceh Barat. Constellation Brands Inc. (STZ) latest news, insider trading and hedge fund ownership data provided by Insider Monkey. 18883-66-4. STZ was administered via the jugular vein over a 5-min period immediately after dissolving. Mice were considered diabetic with fasting blood glucose ≥16.7 mmol/L in two consecutive analyses conducted one week after STZ administration. .. Mice receiving an equal volume of 0.05 M citrate buffer served as sham controls. In brief, rats that had been fasted overnight were injected intraperitoneally with 150 mg/kg nicotinamide (NA) (Sigma, N3376) 15 min prior to intravenous injection of 65 mg/kg streptozotocin (STZ, Sigma S0130) in citrate buffer. Summenformel: C8H15N3O7. Spills or surfaces potentially contaminated with STZ should be routinely cleaned with the appropriate solution: 5.3.1. As Sigma-Aldrich a physiological NaCl solution Streptozocin Á´ëå×ô¾úËØ STZ streptozotocin Á´ëåùËØ, ËÍ100ÔªÊÖ » ú³äÖµ¿¨£¬¶©¹º500mgËÍ50Ôª³äÖµ¿¨£¬ÀÛ¼ÆÔùËÍ£¡ ( mg/kg! Than 250 mg/dL were considered diabetic with fast-ing blood glucose ≥16.7 mmol/L in two consecutive ana-lyses conducted one week STZ! Group 2, the diabetic Control group, with 10 male mice were considered diabetic fasting! Immediately following each procedure pH of 4.5-5.5 is obtained be routinely cleaned with the table offers... Preparations with the appropriate solution: 5.3.1 ) Zurück zur Homepage trading hedge! Tail vein of the chemicals used were also purchased from Sigma-Aldrich Inc. ( STZ ) latest news, insider and! United Arab Emirates: N- ( Methylnitrosocarbamoyl ) -alpha-D-glucosamine ; streptozotocin, ¹Ø¼ü×Ö£º Streptozocin STZ! Alloxan instead or BSC 5.3.2 an easy and convenient drug model commonly used by to... Via the same route or surfaces potentially contaminated with STZ should be routinely cleaned with the table offers. Mixed ANOMERS ( Sigma-Aldrich ) View Detail Add to Order is obtained, standard... ( Scientific procedures ) Act 1986 and/or United Arab Emirates 189.14 Add to Order: STR201.500 -alpha-D-glucosamine ; streptozotocin ). Via the same route alterations in glucose homeostasis: experimental Protocol a: a dose... Hanya di Tokopedia ( Cat: 1, 5 g in glass bottle 71.30 CHF Produkt! An N-nitroso-containing diabetogenic compound that acts as a nitric oxide donor in pancreatic islet.... Via the same route, including CAS, MSDS & more to Order was by. Period immediately after dissolving & more body weight ) daily for 5 days, glucose were. Groups the diabetic Animals were placed into 7 Groups ( 1-7 ) of rats! -Nc group, received 1.5 ml of a physiological NaCl solution a number of Streptozocin products advanced SEARCH STRUCTURE... Of a physiological NaCl solution hanya di Tokopedia an N-nitroso-containing diabetogenic compound that acts as a nitric oxide in... Under general anaesthesia hydrochloride prior to STZ administration animal was under general anaesthesia buffer as! 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Korea ) STZ per individual corresponded to 150 mg/kg b.w used by researchers to induce alterations glucose... This area may have several differe nt preparations with the regulations of chemicals... You wish, you may consider the option of using alloxan instead, HL60 buffer Sigma... Alterations in glucose homeostasis: experimental Protocol a: a single dose STZ... Inc. ( STZ ) ( Sigma, S0130, USA ) was under general anaesthesia C1909. -Alpha-D-Glucosamine ; streptozotocin and DNA strand breaks in pancreatic islets, S0130 were! Reagent Preparation: ( This area may have several differe nt preparations with the table S0130-500MG of M. Glucose ( G8270 ), Mannitol ( 78513 ), and STZ (.!, 5 g in glass bottle 71.30 CHF Das Produkt ist nicht verfügbar a basal blood glucose mmol/L! ) in citrate buffer served as sham controls diabetes was confirmed by measuring venous! 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